Blog - In Vitro Studies

In Vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129)

In Vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129)

In Vitro Cytotoxicity in Balb/c 3T3 LD50 (OECD 129) The in vitro cytotoxicity assay in Balb/c 3T3 cells with an LD50 endpoint (OECD 129) is a test method used to determine the cytotoxic potential of chemicals towards mammalian cells. This information can be helpful

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Study Design of In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428)

Study Design of In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428)

Study Design of In Vitro Skin Absorption: Franz Cell Diffusion Assay (OECD 428) The Franz Cell Diffusion Assay (OECD 428) is a well-established and standardized in vitro method for assessing the percutaneous absorption of chemicals through human skin. It mimics the passive diffusion of chemicals across

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Study Design of EpiSkin-In Vitro Skin Corrosion (OECD 431)

Study Design of EpiSkin-In Vitro Skin Corrosion (OECD 431)

Study Design of EpiSkin-In Vitro Skin Corrosion (OECD 431) The EpiSkin-In Vitro Skin Corrosion Test, based on the OECD Guideline 431, is a validated, non-animal alternative for assessing the corrosive potential of chemicals and mixtures. It utilizes reconstructed human epidermis

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Study Design of In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437)

Study Design of In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437)

Study Design of In Vitro Eye Irritation [Bovine Corneal Opacity and Permeability (BCOP) Test] (OECD 437) The In Vitro Eye Irritation Test using the Bovine Corneal Opacity and Permeability (BCOP) method, outlined in OECD Guideline 437, is an alternative to

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Study Design of EpiSkin-In Vitro Skin Irritation (OECD 439)

Study Design of EpiSkin-In Vitro Skin Irritation (OECD 439)

Study Design of EpiSkin-In Vitro Skin Irritation (OECD 439) The EpiSkin-In Vitro Skin Irritation Test, based on the OECD Guideline 439, is another validated alternative to animal testing for assessing the irritating potential of chemicals and mixtures. It utilizes reconstructed

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Study Design of In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C)

Study Design of In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C)

Study Design of In Vitro Skin Sensitization [Dermal Peptide Reactivity Assay (DPRA)] (OECD 442C) The Dermal Peptide Reactivity Assay (DPRA) is an in chemico assay used to assess the skin sensitization potential of chemicals. It is based on the principle that skin

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