Test No. 202: Daphnia sp. Acute Immobilisation Test “OECD 202” actually refers to the Daphnia sp. Acute Immobilisation Test, a standard laboratory procedure used to assess the short-term toxicity of chemicals to freshwater invertebrates like Daphnia. Here’s what you need to know about OECD 202: What it does: Measures the acute (short-term) effects of a substance […]
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Test No. 310: Ready Biodegradability – CO2 in sealed vessels (Headspace Test) Purpose: This test determines if a chemical is readily biodegradable under aerobic conditions (meaning in the presence of oxygen). This knowledge is crucial for assessing the chemical’s potential persistence and environmental impact. Method: The test substance is incubated in sealed bottles containing a buffer-mineral salts
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Test No. 306: Biodegradability in Seawater The OECD 306 Guideline describes two methods for assessing the biodegradability of organic materials in seawater: Importance of Seawater Biodegradability Testing: Understanding how chemicals break down in marine environments is crucial for protecting the health of our oceans and the organisms that live there. This test helps predict the fate
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Test No. 304A: Inherent Biodegradability in Soil The OECD 304 actually refers to two distinct test guidelines, both focused on assessing the biodegradability of chemicals in soil: 1. OECD 304A: Inherent Biodegradability in Soil This test evaluates the mineralization rate of a 14C-labeled test substance in soil. It measures the rate at which the organic carbon content of the test substance
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Test No. 301: Ready Biodegradability It’s actually not just one test, but a group of six related test guidelines for assessing the ready biodegradability of chemicals in an aerobic aqueous medium. Each method has its own strengths and weaknesses, and the choice of which method to use depends on the specific properties of the test substance.
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Acute Toxicity Studies – Study Design of OECD Guideline 420: Acute Oral Toxicity – Fixed Dose Method The OECD Guideline 420 outlines the study design for the Acute Oral Toxicity – Fixed Dose Method, an in vivo test used to assess the potential harm of a substance following a single oral administration. Here’s a breakdown of
Acute Toxicity Studies – Study Design of OECD 423 Acute Oral The OECD 423 Acute Oral Toxicity Test Guideline is a stepwise procedure used to determine the acute oral toxicity of a substance in rodents, typically rats. It is designed to minimize the number of animals used while providing enough information to classify the substance
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Acute Toxicity Studies – Study Design of OECD Guideline 425: Acute oral toxicity – up and down procedure The OECD Guideline 425 outlines the study design for the Acute Oral Toxicity – Up-and-Down Procedure, another method for assessing the potential harm of a substance following a single oral administration. Here’s a breakdown of its key aspects:
Acute Toxicity Studies – Study Design of OECD Guideline 402: Acute Dermal Toxicity Study in Rats The OECD Guideline 402 outlines the study design for assessing the acute dermal toxicity of chemicals in rats. This information is crucial for ensuring the safety of chemicals before they enter the market. Here’s a breakdown of the key
Acute Toxicity Studies – Study Design of Acute Inhalation Study in Rats (OECD 403) The OECD Guideline 403 outlines the study design for assessing the acute inhalation toxicity of chemicals in rats. This information is crucial for ensuring the safety of chemicals before they enter the market. Here’s a breakdown of the key aspects: Objectives:
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